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lurasidone

lurasidone

商品货号:CC5870 用户评价: comment rank 5

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¥516.00元
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产品描述:

Lurasidone is a second-generation antipsychotic agent that exhibits full antagonism at dopamine D2 and serotonin 5-HT2A receptors with binding affinities Ki = 1 nM and Ki = 0.5 nM, respectively. It also has high affinity for serotonin 5-HT7 receptors (Ki = 0.5 nM), partial agonist activity at 5-HT1A receptors (Ki = 6.4 nM) and lacks affinity for histamine H1 and muscarinic M1 receptors.

化学数据:

分子量Molecular Weight (MW) 492.68
化学式Formula

 

C28H36N4O2S

 

CAS号CAS No. 367514-87-2
溶解性Solubility (25°C) *  二甲基亚砜DMSO 7 mg/mL(14.2 mM)
水Water Insoluble
乙醇Alcohol Insoluble


制备储备液

浓度 溶剂体积(DMSO) 质量 1 mg 5 mg 10 mg
1 mM 2.0297 mL 10.1486 mL 20.2972 mL
5 mM 0.4059 mL 2.0297 mL 4.0594 mL
10 mM 0.2030 mL 1.0149 mL 2.0297 mL
50 mM - - -


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